Sevelamer does not have a distinct melting point. Differential Scanning Calorimetry
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چکیده
Treatment of hyperphosphataemia consists of dietary phosphorus restriction and/or dialysis and phosphate binders. Almost all dialysis patients require phosphate binders (calcium acetate, calcium carbonate, aluminium hydroxide). The use of calcium-based phosphate binders can result in chronic calcium overload, hypercalcemia and soft tissue calcification. Hypercalcemia is particularly common in patients treated with calcitriol and other vitamin D analogues. Aluminium-based phosphate binders are associated with significant toxicity due to small amounts of absorbed aluminium (encephalopathy, osteomalacia, myopathy).
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